Dataset Information

Masson Tumor in the Left Atrial Appendage Presenting as Cardioembolic Cerebral Infarction.

ABSTRACT: A 70-year-old woman presented with aphasia caused by acute infarction in the left middle cerebral artery. Cardiac investigation revealed progressively increasing mobile mass in the left atrial appendage over 2 months (from 9 to 15 mm). Decision was made to proceed with mass resection, and pathological evaluation confirmed Masson tumor. (Level of Difficulty: Advanced.).

SUBMITTER: Mantha Y

PROVIDER: S-EPMC8299123 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Masson Tumor in the Left Atrial Appendage Presenting as Cardioembolic Cerebral Infarction.

Mantha Yogamaya Y Harada Rakushumimarika R Hieda Michinari M Assaf Andrew A Tatiraju Uday U Feldman Mark M Kawalsky Darryl D

JACC. Case reports 20200722 12

A 70-year-old woman presented with aphasia caused by acute infarction in the left middle cerebral artery. Cardiac investigation revealed progressively increasing mobile mass in the left atrial appendage over 2 months (from 9 to 15 mm). Decision was made to proceed with mass resection, and pathological evaluation confirmed Masson tumor. (<b>Level of Difficulty: Advanced.</b>). ...[more]

PMID: 34317091

Similar Datasets

Project description:BackgroundLeft atrial (LA) myopathy is thought to be associated with silent brain infarctions (SBI) through changes in blood flow hemodynamics leading to thrombogenesis. 4D-flow MRI enables in-vivo hemodynamic quantification in the left atrium (LA) and LA appendage (LAA).PurposeTo determine whether LA and LAA hemodynamic and volumetric parameters are associated with SBI.Study typeProspective observational study.PopulationA single-site cohort of 125 Participants of the multiethnic study of atherosclerosis (MESA), mean age: 72.3 ± 7.2 years, 56 men.Field strength/sequence1.5T. Cardiac MRI: Cine balanced steady state free precession (bSSFP) and 4D-flow sequences. Brain MRI: T1- and T2-weighted SE and FLAIR.AssessmentPresence of SBI was determined from brain MRI by neuroradiologists according to routine diagnostic criteria in all participants without a history of stroke based on the MESA database. Minimum and maximum LA volumes and ejection fraction were calculated from bSSFP data. Blood stasis (% of voxels <10 cm/sec) and peak velocity (cm/sec) in the LA and LAA were assessed by a radiologist using an established 4D-flow workflow.Statistical testsStudent's t test, Mann-Whitney U test, one-way ANOVA, chi-square test. Multivariable stepwise logistic regression with automatic forward and backward selection. Significance level P < 0.05.Results26 (20.8%) had at least one SBI. After Bonferroni correction, participants with SBI were significantly older and had significantly lower peak velocities in the LAA. In multivariable analyses, age (per 10-years) (odds ratio (OR) = 1.99 (95% confidence interval (CI): 1.30-3.04)) and LAA peak velocity (per cm/sec) (OR = 0.87 (95% CI: 0.81-0.93)) were significantly associated with SBI.ConclusionOlder age and lower LAA peak velocity were associated with SBI in multivariable analyses whereas volumetric-based measures from cardiac MRI or cardiovascular risk factors were not. Cardiac 4D-flow MRI showed potential to serve as a novel imaging marker for SBI.Level of evidence3 TECHNICAL EFFICACY: Stage 2.

Dataset Information

Masson Tumor in the Left Atrial Appendage Presenting as Cardioembolic Cerebral Infarction.

Publications

Masson Tumor in the Left Atrial Appendage Presenting as Cardioembolic Cerebral Infarction.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets