The effect of high-dose parenteral vitamin D₃ on COVID-19-related inhospital mortality in critical COVID-19 patients during intensive care unit admission: an observational cohort study.

ABSTRACT:

Background

In many studies, vitamin D has been found to be low in COVID-19 patients. In this study, we aimed to investigate the relationship between clinical course and inhospital mortality with parenteral administration of high-dose vitamin D₃ within the first 24 h of admission to patients who were hospitalized in the intensive care unit (ICU) because of COVID-19 with vitamin D deficiency.

Methods

This study included 175 COVID-19 patients with vitamin D deficiency [25(OH) D <12 ng/mL] who were hospitalized in the ICU. Vitamin D₃ group (n = 113) included patients who received a single dose of 300,000 IU vitamin D3 intramuscularly. Vitamin D₃ was not administered to the control group (n = 62).

Results

Median C-reactive protein level was

SUBMITTER: Guven M 

PROVIDER: S-EPMC8299443 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature