Assessment of TSLP, IL 25 and IL 33 in patients with shrimp allergy.

ABSTRACT:

Background

Shrimp allergy is a growing problem among the European population. TSLP, IL-25 and IL-33 are involved in the pathophysiology of allergic diseases, including asthma and atopic dermatitis, as they activate the Th2-dependent immune response.

Methods

Thirty-seven patients (18 male and 19 female) with a positive history of symptoms associated with shrimp consumption were selected. All patients had blood samples taken to assess the concentration of allergen-specific IgE (sIgE) to house dust mites (HDM) and shrimp (Singleplex, quantitative method with cut off value > 0,35 kAU/L) as well as the level of allergen components using the ImmunoCap ISAC method (Microarray test, semi-quantitative with cut off value > 0,3 ISU-E). The concentrations of TSLP, IL-25 and IL-33 in the

SUBMITTER: Ukleja-Sokolowska N 

PROVIDER: S-EPMC8299623 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature