Global prevalence of long-term neurodevelopmental impairment following extremely preterm birth: a systematic literature review.

ABSTRACT:

Objective

Neurodevelopmental impairment (NDI) is a major complication of extreme prematurity. This systematic review was conducted to summarize the worldwide long-term prevalence of NDI associated with extreme prematurity.

Methods

Embase and MEDLINE databases were searched for epidemiologic and observational/real-world studies, published in English between 2011 and 2016, reporting long-term prevalence of NDI (occurring from 1 year) among extremely preterm infants born at gestational age (GA) ≤28 weeks.

Results

Of 2406 articles identified through searches, 69 met the protocol NDI definition (24 North America, 25 Europe, 20 Rest of World). Prevalence of any severity NDI in North America was 8%-59% at 18 months to 2 years, and 11%-37% at 2-5 years; prevalence of moderate

SUBMITTER: Sarda SP 

PROVIDER: S-EPMC8299900 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature