Developing Recommendations for Cumulative Endpoints and Lifetime Use for Research Animals.

ABSTRACT: Research animals are important for scientific advancement, and therefore, their long-term welfare needs to be monitored to not only minimize suffering, but to provide positive affective states and experiences. Currently, there is limited guidance in countries around the world on cumulative and experimental endpoints. This paper aims to explore current opinions and institutional strategies regarding cumulative use and endpoints through a scoping survey and review of current regulations and welfare assessment tools, and ultimately to provide recommendations for assessment of cumulative and lifetime use of research animals. The survey found that only 36% of respondents indicated that their institution had cumulative use endpoint policies in place, but these policies may be informal and/or var

SUBMITTER: Nunamaker EA 

PROVIDER: S-EPMC8300189 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature