Efficacy and safety of potential vaccine candidates against coronavirus disease 2019: A systematic review.

ABSTRACT: Search for an effective and safe vaccine to prevent transmission of current pandemic is an unmet need. This study reviews and compares the available early phase clinical data of vaccine candidates which have reached phase 3 of clinical development. The latest update of "DRAFT landscape of coronavirus (CoV) disease 2019 candidate vaccines (October 2, 2020)" released by the World Health Organization was accessed to identify the potential vaccine candidates. The full text articles (published and/or preprint) of data of early clinical trials of the selected vaccines were accessed from the links provided in the same document, PubMed and/or medRxiv.com. After extraction and synthesis, the data were critically evaluated for the study efficacy and safety outcomes. Of the total 193 candidate vaccin

SUBMITTER: Kumar S 

PROVIDER: S-EPMC8300322 | biostudies-literature | 2021 Jul-Sep

REPOSITORIES: biostudies-literature