Electroencephalography and Event-Related Potential Biomarkers in Individuals at Clinical High Risk for Psychosis.

ABSTRACT: Clinical outcomes vary among youths at clinical high risk for psychosis (CHR-P), with approximately 20% progressing to full-blown psychosis over 2 to 3 years and 30% achieving remission. Recent research efforts have focused on identifying biomarkers that precede psychosis onset and enhance the accuracy of clinical outcome prediction in CHR-P individuals, with the ultimate goal of developing staged treatment approaches based on the individual's level of risk. Identifying such biomarkers may also facilitate progress toward understanding pathogenic mechanisms underlying psychosis onset, which may support the development of mechanistically informed early interventions for psychosis. In recent years, electroencephalography-based event-related potential measures with established sensitivity to s

SUBMITTER: Hamilton HK 

PROVIDER: S-EPMC8300573 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature