Endothelial Function and Oxidative Stress in X-Linked, gp91^phox Deficiency, Chronic Granulomatous Disease.

ABSTRACT: Two patients with X-linked chronic granulomatous disease without NAPDH oxidase activity and with high responses of flow-mediated vasodilation are reported. Bone marrow transplantation restored oxidative stress to the levels of those in healthy subjects and decreased flow-mediated vasodilation to the levels of those in healthy subjects in both of the patients. (Level of Difficulty: Advanced.).

SUBMITTER: Higashi Y 

PROVIDER: S-EPMC8302114 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature