Impact of Physical Activity on Oxidative Stress Markers in Patients with Metastatic Breast Cancer.

ABSTRACT:

Purpose

Regular physical activity (PA) can affect oxidative stress, known to be involved in carcinogenesis. The objective of this study was to evaluate the associations between a six-month PA intervention and oxidative stress biomarkers, PA, and clinical outcomes in patients with metastatic breast cancer.

Methods

Forty-nine newly diagnosed patients with metastatic breast cancer were recruited for a single-arm, unsupervised, and personalized six-month walking intervention with activity tracker. PA level and PA fitness, plasma concentrations of DNA oxidation (8OhdG), lipid peroxidation (MDA), and protein oxidation (AOPP), plasma activities of superoxide dismutase (SOD), glutathione peroxidase (GPX), and catalase, plasma and leucocyte activities of myeloperoxidase (MPO) and NAD

SUBMITTER: Delrieu L 

PROVIDER: S-EPMC8302399 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature