Fat-enlarged axillary lymph nodes are associated with node-positive breast cancer in obese patients.

ABSTRACT:

Purpose

Obesity associated fat infiltration of organ systems is accompanied by organ dysfunction and poor cancer outcomes. Obese women demonstrate variable degrees of fat infiltration of axillary lymph nodes (LNs), and they are at increased risk for node-positive breast cancer. However, the relationship between enlarged axillary nodes and axillary metastases has not been investigated. The purpose of this study is to evaluate the association between axillary metastases and fat-enlarged axillary nodes visualized on mammograms and breast MRI in obese women with a diagnosis of invasive breast cancer.

Methods

This retrospective case-control study included 431 patients with histologically confirmed invasive breast cancer. The primary analysis of this study included 306 patients wi

SUBMITTER: diFlorio-Alexander RM 

PROVIDER: S-EPMC8302552 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature