Prognosis of French COVID-19 patients with chronic liver disease: A national retrospective cohort study for 2020.

ABSTRACT:

Background & aims

The impact of chronic liver disease on outcomes in patients with COVID-19 is uncertain. Hence, we aimed to explore this association.

Methods

We explored the outcomes of all adult inpatients with COVID-19 in France, in 2020. We computed adjusted odds ratios to measure the associations between chronic liver disease, alcohol use disorders, mechanical ventilation and day-30 in-hospital mortality.

Results

The sample comprised 259,110 patients (median [IQR] age 70 (54-83) years; 52% men), including 15,476 (6.0%) and 10,006 (3.9%) patients with chronic liver disease and alcohol use disorders, respectively. Death occurred in 38,203 (15%) patients, including 7,475 (28%) after mechanical ventilation, and 2,941 (19%) with chronic liver disease. The adjusted odd

SUBMITTER: Mallet V 

PROVIDER: S-EPMC8302931 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature