Effect of Intermittent Hypoxia on Metabolic Syndrome and Insulin Resistance in the General Male Population.

ABSTRACT: Background and objectives: Obstructive sleep apnea (OSA) is closely associated with insulin resistance (IR) and is an independent risk factor for incident type 2 diabetes mellitus (T2DM). Most studies evaluate the correlation between OSA and IR in only obese or T2DM patients. Therefore, we tried to investigate the effect of OSA on metabolic syndrome and IR in the general healthy male population. Materials and Methods: 184 subjects who visited a preventive health examination program were recruited for this study. All subjects received overnight polysomnography by a portable device (Watch-PAT 200). We examined several metabolic parameters and a homeostasis model of assessment for insulin resistance index (HOMA-IR). The subjects were divided into three groups by AHI (Apnea-hyponea index): nor

SUBMITTER: Lee JY 

PROVIDER: S-EPMC8303242 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature