Cyclohumulanoid Sesquiterpenes from the Culture Broth of the Basidiomycetous Fungus <i>Daedaleopsis tricolor</i>.

ABSTRACT: A series of cyclohumulanoids, i.e., tricocerapicanols A-C (1a-1c), tricoprotoilludenes A (2a) and B (3), tricosterpurol (4), and tricoilludins A-C (5-7) were isolated along with known violascensol (2b) and omphadiol (8) from the culture broth of Daedaleopsis tricolor, an inedible but not toxic mushroom. The structures were fully elucidated on the basis of NMR spectroscopic analysis, and the suggested relative structures were confirmed via density functional theory (DFT)-based chemical shift calculations involving a DP4 probability analysis. In the present study, the ¹H chemical shifts were more informative than the ¹³C chemical shifts to distinguish the diastereomers at C-11. The absolute configurat

SUBMITTER: Kanehara R 

PROVIDER: S-EPMC8303491 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature