Influence of Tunneled Hemodialysis-Catheters on Inflammation and Mortality in Dialyzed Patients.

ABSTRACT: Older age and comorbidities in hemodialysis patients determines the use of tunneled catheters as vascular access despite their reported clinical and mortality disadvantages. This prospective matched study analyzes the impact of permanent catheters on inflammation and mortality in hemodialysis patients; We studied 108 patients, 54 with AV-fistula (AVF) and 54 with indwelling hemodialysis catheters (HDC) matched by sex, age, diabetes and time under renal-replacement therapy comparing dialysis efficacy, inflammation and micro-inflammation parameters as well as mortality. Cox-regression analysis was applied to determine predictors of mortality, HDC patients presented higher C-reactive-protein (CRP) blood levels and percentage of pro-inflammatory lymphocytes CD14+/CD16+ with worse dialysis-effi

SUBMITTER: Crespo-Montero R 

PROVIDER: S-EPMC8304695 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature