Disrupted Functional Rich-Club Organization of the Brain Networks in Children with Attention-Deficit/Hyperactivity Disorder, a Resting-State EEG Study.

ABSTRACT: Growing evidence indicates that disruptions in the brain's functional connectivity play an important role in the pathophysiology of ADHD. The present study investigates alterations in resting-state EEG source connectivity and rich-club organization in children with inattentive (ADHD_I) and combined (ADHD_C) ADHD compared with typically developing children (TD) under the eyes-closed condition. EEG source analysis was performed by eLORETA in different frequency bands. The lagged phase synchronization (LPS) and graph theoretical metrics were then used to examine group differences in the topological properties and rich-club organization of functional networks. Compared with the TD children, the ADHD_I children were characterized by a widespread significant decreas

SUBMITTER: Ahmadi M 

PROVIDER: S-EPMC8305540 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature