ESI-MS/MS Analysis of Phenolic Compounds from Aeonium arboreum Leaf Extracts and Evaluation of their Antioxidant and Antimicrobial Activities.

ABSTRACT: Aeonium is a genus of succulents belonging to the Crassulaceae family. Their importance in traditional medicine has stimulated both pharmacological and chemical research. In this study, we optimized extraction, separation, and analytical conditions using a high performance liquid chromatographic method coupled with electrospray ionization mass spectrometry by the negative mode (HPLC-ESI-MS) in order to, for the first time, determine thirty-four compounds from Aeonium arboreum leaves. Twenty-one of them are assigned among which are sixteen flavonoids and five phenolic acids. FRAP, TAC, DPPH, and ABTS^•+ radical scavenging were used to evaluate antioxidant activity. The obtained IC₅₀ values ranged from 0.031 to 0.043 mg.mL^-1 for DPPH and between

SUBMITTER: Affes S 

PROVIDER: S-EPMC8306197 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature