Current Concepts of Stem Cell Therapy for Chronic Spinal Cord Injury.

ABSTRACT: Chronic spinal cord injury (SCI) is a catastrophic condition associated with significant neurological deficit and social and financial burdens. It is currently being managed symptomatically with no real therapeutic strategies available. In recent years, a number of innovative regenerative strategies have emerged and have been continuously investigated in clinical trials. In addition, several more are coming down the translational pipeline. Among ongoing and completed trials are those reporting the use of mesenchymal stem cells, neural stem/progenitor cells, induced pluripotent stem cells, olfactory ensheathing cells, and Schwann cells. The advancements in stem cell technology, combined with the powerful neuroimaging modalities, can now accelerate the pathway of promising novel therapeutic

SUBMITTER: Suzuki H 

PROVIDER: S-EPMC8308009 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature