Ontology highlight
ABSTRACT:
SUBMITTER: McCoubrey LE
PROVIDER: S-EPMC8308984 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
McCoubrey Laura E LE Elbadawi Moe M Orlu Mine M Gaisford Simon S Basit Abdul W AW
Pharmaceutics 20210706 7
The human gut microbiome, composed of trillions of microorganisms, plays an essential role in human health. Many factors shape gut microbiome composition over the life span, including changes to diet, lifestyle, and medication use. Though not routinely tested during drug development, drugs can exert profound effects on the gut microbiome, potentially altering its functions and promoting disease. This study develops a machine learning (ML) model to predict whether drugs will impair the growth of ...[more]