Polymeric Biomaterials for the Treatment of Cardiac Post-Infarction Injuries.

ABSTRACT: Cardiac regeneration aims to reconstruct the heart contractile mass, preventing the organ from a progressive functional deterioration, by delivering pro-regenerative cells, drugs, or growth factors to the site of injury. In recent years, scientific research focused the attention on tissue engineering for the regeneration of cardiac infarct tissue, and biomaterials able to anatomically and physiologically adapt to the heart muscle have been proposed as valuable tools for this purpose, providing the cells with the stimuli necessary to initiate a complete regenerative process. An ideal biomaterial for cardiac tissue regeneration should have a positive influence on the biomechanical, biochemical, and biological properties of tissues and cells; perfectly reflect the morphology and functionality

SUBMITTER: Trombino S 

PROVIDER: S-EPMC8309168 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature