Lubricating properties of chewing stimulated whole saliva from patients suffering from xerostomia.

ABSTRACT:

Objectives

The study aimed to quantify the lubricating properties of chewing stimulated whole saliva from healthy controls (n = 22), from patients suffering from primary Sjögren's syndrome (n = 37) and from patients undergoing head-and-neck radiotherapy (n = 34).

Materials and methods

All participants had to complete the Xerostomia Inventory questionnaire to score dry mouth sensation. Lubrication was measured using an ex vivo tongue-enamel friction system in terms of Relief and Relief period. MUC5b and total protein concentrations of the saliva samples were measured by an enzyme-linked immunosorbent assay and a bicinchoninic acid assay, respectively.

Results

Relief of Sjögren's patients' saliva and post-irradiation patients' saliva was similar compared with healthy co

SUBMITTER: Vinke J 

PROVIDER: S-EPMC8310523 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature