Aggression subtypes relate to distinct resting state functional connectivity in children and adolescents with disruptive behavior.

ABSTRACT: There is increasing evidence for altered brain resting state functional connectivity in adolescents with disruptive behavior. While a considerable body of behavioral research points to differences between reactive and proactive aggression, it remains unknown whether these two subtypes have dissociable effects on connectivity. Additionally, callous-unemotional traits are important specifiers in subtyping aggressive behavior along the affective dimension. Accordingly, we examined associations between two aggression subtypes along with callous-unemotional traits using a seed-to-voxel approach. Six functionally relevant seeds were selected to probe the salience and the default mode network, based on their presumed role in aggression. The resting state sequence was acquired from 207 children an

SUBMITTER: Werhahn JE 

PROVIDER: S-EPMC8310860 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature