Mass Drug Administration With Artemisinin-Piperaquine for the Elimination of Residual Foci of Malaria in Sao Tome Island.

ABSTRACT: Background: Mass drug administration with artemisinin-piperaquine (AP-MDA) is being considered for elimination of residual foci of malaria in Democratic Republic of São Tomé and Principe. Methods: Three monthly rounds of AP-MDA were implemented from July to October 2019. Four zones were selected. A and B were selected as a study site and a control site, respectively. C and D were located within 1.5 and 1.5 km away from the study site, respectively. Parasite prevalence, malaria incidence, and the proportion of the Plasmodium falciparum malaria cases were evaluated. Results: After 3 monthly rounds of AP-MDA, the parasite prevalence and the gametocyte carriage rate of P. falciparum in zone A decreased from 28.29(‰) to 0 and 4.99(‰) to 0, respectively. Compar

SUBMITTER: Li M 

PROVIDER: S-EPMC8311023 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature