The role of diffuse correlation spectroscopy and frequency-domain near-infrared spectroscopy in monitoring cerebral hemodynamics during hypothermic circulatory arrests.

ABSTRACT:

Objectives

Real-time noninvasive monitoring of cerebral blood flow (CBF) during surgery is key to reducing mortality rates associated with adult cardiac surgeries requiring hypothermic circulatory arrest (HCA). We explored a method to monitor cerebral blood flow during different brain protection techniques using diffuse correlation spectroscopy (DCS), a noninvasive optical technique which, combined with frequency-domain near-infrared spectroscopy (FDNIRS), also provides a measure of oxygen metabolism.

Methods

We used DCS in combination with FDNIRS to simultaneously measure hemoglobin oxygen saturation (SO₂), an index of cerebral blood flow (CBF_i), and an index of cerebral metabolic rate of oxygen (CMRO_2i) in 12 patients undergoing cardiac sur

SUBMITTER: Zavriyev AI 

PROVIDER: S-EPMC8311503 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature