MicroRNAs and Their Impact on Breast Cancer, the Tumor Microenvironment, and Disparities.

ABSTRACT: Breast cancer is a worldwide health issue as it represents the leading cause of cancer in women and the second-leading cause of cancer-related mortality in women, with an increasing incidence. Nothing speaks more clearly to the shocking breast cancer health disparities than the fact that African American (AA) women are as likely to get breast cancer as Caucasian American (CA) women, yet have a higher breast cancer death rate. It is becoming increasingly apparent that racial disparity in cancer exists due to molecular differences in tumor biology as well as, or in addition to, socioeconomic and standard of care issues (Albain, Unger, Crowley, Coltman, & Hershman, 2009). A greater understanding of the risk factors and biological links associated with breast cancer, will significantly impact

SUBMITTER: Evans-Knowell A 

PROVIDER: S-EPMC8311570 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature