Multiaxial validation of a finite element model of the intervertebral disc with multigenerational fibers to establish residual strain.

ABSTRACT: Finite element models of the intervertebral disc are used to address research questions that cannot be tested through typical experimentation. A disc model requires complex geometry and tissue properties to be accurately defined to mimic the physiological disc. The physiological disc possesses residual strain in the annulus fibrosus (AF) due to osmotic swelling and due to inherently pre-strained fibers. We developed a disc model with residual contributions due to swelling-only, and a multigeneration model with residual contributions due to both swelling and AF fiber pre-strain and validated it against organ-scale uniaxial, quasi-static and multiaxial, dynamic mechanical tests. In addition, we demonstrated the models' ability to mimic the opening angle observed following radial incision of

SUBMITTER: Newman HR 

PROVIDER: S-EPMC8313175 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature