Resistance mechanisms and genetic relatedness among carbapenem-resistant Pseudomonas aeruginosa isolates from three major hospitals in Hanoi, Vietnam (2011-15).

ABSTRACT:

Background

MDR bacteria including carbapenem-resistant Pseudomonas aeruginosa are recognized as an important cause of hospital-acquired infections worldwide. This investigation seeks to determine the molecular characterization and antibiotic resistance genes associated with carbapenem-resistant P. aeruginosa.

Methods

We conducted WGS and phylogenetic analysis of 72 carbapenem-resistant P. aeruginosa isolated from hospital-acquired infection patients from August 2011 to March 2015 in three major hospitals in Hanoi, Vietnam.

Results

We identified three variants of IMP gene, among which bla _IMP-15 was the most frequent (n = 34) in comparison to bla _IMP-26 (n = 2) and bla _IMP-

SUBMITTER: Tran HA 

PROVIDER: S-EPMC8313516 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature