Association between Cardiorespiratory Fitness and Circulating Proteins in 50-Year-Old Swedish Men and Women: a Cross-Sectional Study.

ABSTRACT:

Background and aims

A strong cardiorespiratory fitness is suggested to have beneficial effects on cardiovascular risk; the exact mechanisms underlying the cardioprotective effects of fitness remain uncertain. Our aim was to investigate associations between cardiorespiratory fitness and multiple plasma proteins, in order to obtain insights about physiological pathways associated with the effects of exercise on cardiovascular health.

Methods

In the Prospective investigation of Obesity, Energy and Metabolism (POEM) study (n=444 adults aged 50 years, 50% women), cardiorespiratory fitness was measured by a maximal exercise test on bicycle ergometer with gas exchange (VO₂peak) normalized for body lean mass (dual-energy X-ray absorptiometry (DXA)). We measured 82 cardiov

SUBMITTER: Enarsson M 

PROVIDER: S-EPMC8313632 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature