Characterization of isolated compounds from Morus spp. and their biological activity as anticancer molecules.

ABSTRACT: Introduction: The genus Morus is well known for its medicinal benefits from time immemorial. The present work reported the health-promoting properties of the biologically active molecules present in different species of the genus Morus. Methods: Different solvent extracts of the three plant species of Morus were investigated initially for their antioxidant effects, followed by in vitro anticancer studies against MCF7 and 3T3 cell lines along with their bioactive isolates viz. cathafuran-B, moracin-M, and Ursolic acid. Further, in silico docking studies were performed for the isolated compounds to predict their probable mode of interaction with P38Map Kinase. Results: The results indicated that all three spe

SUBMITTER: Rao Rao Shimoga Janakirama A 

PROVIDER: S-EPMC8314033 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature