Diagnostic accuracy of rapid antigen tests in asymptomatic and presymptomatic close contacts of individuals with confirmed SARS-CoV-2 infection: cross sectional study.

ABSTRACT:

Objective

To assess the diagnostic test accuracy of two rapid antigen tests in asymptomatic and presymptomatic close contacts of people with SARS-CoV-2 infection on day 5 after exposure.

Design

Prospective cross sectional study.

Setting

Four public health service covid-19 test sites in the Netherlands.

Participants

4274 consecutively included close contacts (identified through test-and-trace programme or contact tracing app) aged 16 years or older and asymptomatic for covid-19 when requesting a test.

Main outcome measures

Sensitivity, specificity, and positive and negative predictive values of Veritor System (Beckton Dickinson) and Biosensor (Roche Diagnostics) rapid antigen tests, with reverse-transcriptase polymerase chain reaction (RT-PCR) testing as

SUBMITTER: Schuit E 

PROVIDER: S-EPMC8314145 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature