Hemogram-derived ratios as prognostic markers of ICU admission in COVID-19.

ABSTRACT:

Background

The vast impact of COVID-19 call for the identification of clinical parameter that can help predict a torpid evolution. Among these, endothelial injury has been proposed as one of the main pathophysiological mechanisms underlying the disease, promoting a hyperinflammatory and prothrombotic state leading to worse clinical outcomes. Leukocytes and platelets play a key role in inflammation and thrombogenesis, hence the objective of the current study was to study whether neutrophil-to-lymphocyte ratio (NLR), platelets-to-lymphocyte ratio (PLR), the systemic immune-inflammation index (SII) as well as the new parameter neutrophil-to-platelet ratio (NPR), could help identify patients who at risk of admission at Intensive Care Units.

Methods

A retrospective observational

SUBMITTER: Velazquez S 

PROVIDER: S-EPMC8314257 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature