Association of depressive symptoms and risk of knee pain: the moderating effect of sex.

ABSTRACT:

Background

Depression has been shown in some studies to be associated with knee pain. Females were widely recognized as more vulnerable to depression and knee pain than males. However, the role of sex in this correlation was under-researched. This study aimed to investigate the association between depressive symptoms and subsequent knee pain, as well as whether and how sex would moderate this association based on a four-wave (Wave 1 in 2010-2011, Wave 2 in 2013, Wave 3 in 2015, and Wave 4 in 2018) longitudinal study among middle-aged and elderly Chinese adults.

Methods

Seventeen thousand seven hundred eight participants were recruited and followed in the China Health and Retirement Longitudinal Study (CHARLS). Ten thousand four hundred fifty-one entered the final analysis ba

SUBMITTER: Hu H 

PROVIDER: S-EPMC8314447 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature