Primary tumor surgery improves survival in non-metastatic primary urethral carcinoma patients: a large population-based investigation.

ABSTRACT:

Background

Primary urethral carcinoma (PUC) is a rare genitourinary malignancy with a relatively poor prognosis. The aim of this study was to examine the impact of surgery on survival of patients diagnosed with PUC.

Methods

A total of 1544 PUC patients diagnosed between 2004 and 2016 were identified based on the SEER database. The Kaplan-Meier estimate and the Fine and Gray competing risks analysis were performed to assess overall survival (OS) and cancer-specific mortality (CSM). The multivariate Cox regression model and competing risks regression model were used to identify independent risk factors of OS and cancer-specific survival (CSS).

Results

The 5-yr OS was significantly better in patients who received either local therapy (39.8%) or radical surgery (44.7%) co

SUBMITTER: Wu J 

PROVIDER: S-EPMC8314574 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature