Replication in Human Intestinal Enteroids of Infectious Norovirus from Vomit Samples.
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ABSTRACT:
SUBMITTER: Hagbom M
PROVIDER: S-EPMC8314841 | biostudies-literature | 2021 Aug
REPOSITORIES: biostudies-literature
Publications
Replication in Human Intestinal Enteroids of Infectious Norovirus from Vomit Samples.
Hagbom Marie M Lin Jenny J Falkeborn Tina T Serrander Lena L Albert Jan J Nordgren Johan J Sharma Sumit S
Emerging infectious diseases 20210801 8
A typical clinical symptom of human norovirus infection is projectile vomiting. Although norovirus RNA and viral particles have been detected in vomitus, infectivity has not yet been reported. We detected replication-competent norovirus in 25% of vomit samples with a 13-fold to 714-fold increase in genomic equivalents, confirming infectious norovirus. ...[more]
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