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Prognostic molecular biomarkers in endometrial cancer: A review.


ABSTRACT:

Background

Endometrial cancer (EC) is the fourth most common malignancy in women worldwide and the most common gynecological cancer in developed countries. The endometrioid subtype has an excellent prognosis with conventional treatment; however, recurrence reduces overall survival.

Objective

Describe the most relevant evidence regarding selected potential molecular biomarkers that may predict overall survival (OS), relapse-free survival (RFS), and cancer-specific survival (CSS) in EC.

Methods

An exhaustive search was performed in PUBMED with the search terms endometrial cancer, molecular biomarker, and survival. We selected original articles written in English about endometrial cancer, molecular biomarkers, and that included survival analysis published between January

SUBMITTER: Hernandez JE 

PROVIDER: S-EPMC8315102 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature