Management of clinical chorioamnionitis: an evidence-based approach.

ABSTRACT: This review aimed to examine the existing evidence about interventions proposed for the treatment of clinical chorioamnionitis, with the goal of developing an evidence-based contemporary approach for the management of this condition. Most trials that assessed the use of antibiotics in clinical chorioamnionitis included patients with a gestational age of ≥34 weeks and in labor. The first-line antimicrobial regimen for the treatment of clinical chorioamnionitis is ampicillin combined with gentamicin, which should be initiated during the intrapartum period. In the event of a cesarean delivery, patients should receive clindamycin at the time of umbilical cord clamping. The administration of additional antibiotic therapy does not appear to be necessary after vaginal or cesarean delivery. Howeve

SUBMITTER: Conde-Agudelo A 

PROVIDER: S-EPMC8315154 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature