Thirty percent of children and young adults with familial hypercholesterolemia treated with statins have adherence issues.

ABSTRACT:

Objective

To assess adherence to lipid lowering therapy (LLT), reasons for poor adherence, and achievement of LDL-C treatment goals in children and young adults with familial hypercholesterolemia (FH).

Methods

Retrospective review of the medical records of 438 children that started follow-up at the Lipid Clinic, Oslo University hospital, between 1990 and 2010, and followed-up to the end of July 2019. Based on information on adherence to the LLT at the latest visit, patients were assigned to "good adherence" or "poor adherence" groups. Reasons for poor adherence were categorized as: "lack of motivation", "ran out of drugs", or "side effects".

Results

Three hundred and seventy-one patients were included. Mean (SD) age and follow-up time at the latest visit was 24.0 (7.1

SUBMITTER: Langslet G 

PROVIDER: S-EPMC8315460 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature