The risk of cardiometabolic disorders in lean non-alcoholic fatty liver disease: A longitudinal study.

ABSTRACT:

Background

Recent studies suggest that non-alcoholic fatty liver disease (NAFLD) in lean (BMI<25 ​kg/m²) individuals presents a distinct phenotype. We sought to determine the cardiometabolic consequences of lean NAFLD in a population cohort of relatively young asymptomatic individuals who participated in a voluntary routine health promotion evaluation in Brazil.

Methods

We analyzed data in our population collected from 2004 to 2016. Medical and demographic history, anthropometric measures, and fasting blood samples were obtained. Participants had ultrasonography to assess for fatty liver. We defined NAFLD as fatty liver in individuals scoring below 8 on the alcohol use disorders identification test (AUDIT). We included data from 9137 individuals who had complete d

SUBMITTER: Aneni EC 

PROVIDER: S-EPMC8315654 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature