Circadian rhythm and gestational diabetes: working conditions, sleeping habits and lifestyle influence insulin dependency during pregnancy.

ABSTRACT:

Objective

Management of gestational diabetes (GDM) is currently changing toward a more personalized approach. There  is a growing number of GDM patients requiring only a single dose of basal insulin at night to achieve glucose control. Well-known risk factors like obesity, parity and family history have been associated with GDM treatment requirements. Sleep quality and lifestyle factors interfering with the circadian rhythm are known to affect glucose metabolism. The aim of this study was to investigate the impact of such lifestyle factors on insulin requirement in GDM patients, in particular on long-acting insulin to control fasting glucose levels.

Research design and methods

A total of 805 patients treated for GDM between 2012 and 2016 received a study questionnaire on lif

SUBMITTER: Weschenfelder F 

PROVIDER: S-EPMC8316165 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature