Sex Differences in Cardiovascular Outcomes in CKD: Findings From the CRIC Study.

ABSTRACT:

Rationale & objective

Cardiovascular events are less common in women than men in general populations; however, studies in chronic kidney disease (CKD) are less conclusive. We evaluated sex-related differences in cardiovascular events and death in adults with CKD.

Study design

Prospective cohort study.

Setting & participants

1,778 women and 2,161 men enrolled in the Chronic Renal Insufficiency Cohort (CRIC).

Exposure

Sex (women vs men).

Outcome

Atherosclerotic composite outcome (myocardial infarction, stroke, or peripheral artery disease), incident heart failure, cardiovascular death, and all-cause death.

Analytical approach

Cox proportional hazards regression.

Results

During a median follow-up period of 9.6 years, we observed 698 atheroscle

SUBMITTER: Toth-Manikowski SM 

PROVIDER: S-EPMC8316276 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature