An implementation science approach to evaluating pathogen whole genome sequencing in public health.

ABSTRACT:

Background

Pathogen whole genome sequencing (WGS) is being incorporated into public health surveillance and disease control systems worldwide and has the potential to make significant contributions to infectious disease surveillance, outbreak investigation and infection prevention and control. However, to date, there are limited data regarding (i) the optimal models for integration of genomic data into epidemiological investigations and (ii) how to quantify and evaluate public health impacts resulting from genomic epidemiological investigations.

Methods

We developed the Pathogen Genomics in Public HeAlth Surveillance Evaluation (PG-PHASE) Framework to guide examination of the use of WGS in public health surveillance and disease control. We illustrate the use of this framewor

SUBMITTER: Ferdinand AS 

PROVIDER: S-EPMC8317677 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature