Second Primary Cancers After Kidney Cancers, and Kidney Cancers as Second Primary Cancers.

ABSTRACT:

Background

Second primary cancers (SPCs) are increasing due to improving survival in first primary cancers. Previous studies on SPCs in renal cell carcinoma (RCC) have focused on treatment and other risk factors, but data of RCC as an SPC are scarce.

Objective

In this study, we want to elucidate the risk for any SPC after RCC, and in reverse order, for RCC as an SPC after any cancer. We additionally consider how family histories influence the risks.

Design setting and participants

Patient data were obtained from the Swedish Cancer Registry from years 1990 through 2015, and family data were obtained from the Multigeneration Register.

Outcome measurements and statistical analysis

We employed standardized incidence ratios to estimate bidirectional relative risks o

SUBMITTER: Zheng G 

PROVIDER: S-EPMC8317822 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature