Interactions between staphylococcal enterotoxins A and D and superantigen-like proteins 1 and 5 for predicting methicillin and multidrug resistance profiles among Staphylococcus aureus ocular isolates.

ABSTRACT:

Background

Methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant (MDR) S. aureus strains are well recognized as posing substantial problems in treating ocular infections. S. aureus has a vast array of virulence factors, including superantigens and enterotoxins. Their interactions and ability to signal antibiotics resistance have not been explored.

Objectives

To predict the relationship between superantigens and methicillin and multidrug resistance among S. aureus ocular isolates.

Methods

We used a DNA microarray to characterize the enterotoxin and superantigen gene profiles of 98 S. aureus isolates collected from common ocular sources. The outcomes contained phenotypic and genotypic expressions of MRSA. We also included the MDR status as an outcom

SUBMITTER: Lu M 

PROVIDER: S-EPMC8318242 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature