Can lung ultrasound score accurately predict the need for surfactant  replacement in preterm neonates? A systematic review and meta-analysis protocol.

ABSTRACT: Respiratory distress syndrome (RDS) is a leading cause of morbidity and mortality in preterm infants due to primary surfactant deficiency. Surfactant replacement has greatly improved the short and long term prognosis of RDS but its administration criteria remain uncertain. Lung ultrasound has been recently shown as a non-invasive, repeatable, bedside tool to estimate parenchymal aeration using a semiquantitative score (LUS). The objective of this systematic review and meta-analysis is to evaluate the accuracy of LUS, assessed on the first day of life, to predict surfactant replacement. Methods will follow the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) guidelines and the protocol has been registered in PROSPERO database (registration number: CRD42

SUBMITTER: Capasso L 

PROVIDER: S-EPMC8318286 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature