Parathormone levels add prognostic ability to N-terminal pro-brain natriuretic peptide in stable coronary patients.

ABSTRACT:

Aims

There are controversial data on the ability of the components of mineral metabolism (vitamin D, phosphate, parathormone [PTH], fibroblast growth factor-23 [FGF23], and klotho) to predict cardiovascular events. In addition, it is unknown whether they add any prognostic value to other well-known biomarkers.

Methods and results

In 969 stable coronary patients, we determined plasma levels of all the aforementioned components of mineral metabolism with a complete set of clinical and biochemical variables, including N-terminal pro-brain natriuretic peptide (NT-proBNP), high-sensitivity troponin I (hs-TnI), and high-sensitivity C-reactive protein. Secondary outcomes were ischaemic events (any acute coronary syndrome, stroke, or transient ischaemic attack) and heart failure or

SUBMITTER: Gutierrez-Landaluce C 

PROVIDER: S-EPMC8318437 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature