Left ventricular remodelling and prognosis after discharge in new-onset acute heart failure with reduced ejection fraction.

ABSTRACT:

Aims

This study aimed to investigate the left ventricular (LV) remodelling and long-term prognosis of patients with new-onset acute heart failure (HF) with reduced ejection fraction who were pharmacologically managed and survived until hospital discharge. We compared patients with ischaemic and non-ischaemic aetiology.

Methods and results

This cohort study consisted of 111 patients admitted with new-onset acute HF in the period 2008-2016 [62% non-ischaemic aetiology, 48% supported by inotropes, vasopressors, or short-term mechanical circulatory devices, and left ventricular ejection fraction (LVEF) at discharge 28% (interquartile range 22-34)]. LV dimensions, LVEF, and mitral valve regurgitation were used as markers for LV remodelling during up to 3 years of follow-up. Both

SUBMITTER: van den Berge JC 

PROVIDER: S-EPMC8318456 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature