Menopausal symptoms and risk of heart failure: a retrospective analysis from Taiwan National Health Insurance Database.

ABSTRACT:

Aims

Women with menopausal symptoms show evidence of accelerated epigenetic ageing, vascular aging and low-grade systemic inflammation status. However, data are limited regarding menopausal symptoms and risk of heart failure (HF). We aimed to explore the impact of menopausal symptoms on risk of HF.

Methods

We included 14 340 symptomatic menopausal women without a history of coronary heart disease (CHD) or HF from the Taiwan National Health Insurance Research Database as the experimental cohort. We included 14 340 asymptomatic women matched for age and comorbidities as controls. We surveyed possible comorbidity-attributable risks of HF and assessed whether menopausal symptoms play a role in risk of HF. Additional analyses were conducted to ascertain the association of CHD and

SUBMITTER: Huang CH 

PROVIDER: S-EPMC8318496 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature