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Identification of Genomic Regions Influencing N-Metabolism and N-Excretion in Lactating Holstein- Friesians.


ABSTRACT: Excreted nitrogen (N) of dairy cows contribute to environmental eutrophication. The main N-excretory metabolite of dairy cows is urea, which is synthesized as a result of N-metabolization in the liver and is excreted via milk and urine. Genetic variation in milk urea (MU) has been postulated but the complex physiology behind the trait as well as the tremendous diversity of processes regulating the N-metabolism impede the consistent determination of causal regions in the bovine genome. In order to map the genetic determinants affecting N-excretion, MU and eight other N-excretory metabolites in milk and urine were assessed in a genome-wide association study. Therefore phenotypes of 371 Holstein- Friesians were obtained in a trial on a dairy farm under near commercial conditions. Genotype dat

SUBMITTER: Honerlagen H 

PROVIDER: S-EPMC8318802 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature

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