Terpenoids enriched ethanol extracts of aerial roots of Ceriops decandra (Griff.) and Ceriops tagal (Perr.) promote diuresis in mice.

ABSTRACT:

Introduction

Ceriops decandra (CD) and Ceriops tagal (CT) are two traditionally used mangrove plants widely distributed along the coastal areas of South Asia, Africa, South Pacific. In this study, we evaluated the diuretic potential of aerial roots of CD, CT and assessed the effectiveness of the plants' terpenoids enriched bioactive constituents against human carbonic anhydrase (hCA) enzyme through molecular docking.

Materials and methods

Firstly, the acute toxicity of CD and CT was evaluated in mice. In vivo diuretic activity was then studied in mice and the volume of excreted urine was measured. The urine was further examined for pH, density and Na⁺, K⁺, Cl^- concentrations. From this, the saluretic, natriuretic, kaliure

SUBMITTER: Biswas B 

PROVIDER: S-EPMC8318864 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature