Serum metabolome and gut microbiome alterations in broiler chickens supplemented with lauric acid.

ABSTRACT: Antibiotic overuse in poultry husbandry poses a potential threat to meat safety and human health. Lauric acid (LA) is a primary medium-chain fatty acid (MCFA) with a strong antibacterial capacity. The goal of this study was to evaluate the beneficial effects of LA on the growth performance, immune responses, serum metabolism, and cecal microbiota of broiler chickens. One-day-old male Ross 308 broilers were randomly divided into 4 groups: CON, fed a basal diet; ANT, a basal diet supplemented with 75 mg/kg antibiotic; LA₅₀₀, a basal diet supplemented with 500 mg/kg LA; LA₁₀₀₀, a basal diet supplemented with 1000 mg/kg LA. The feeding period was 42 d. The results showed that LA significantly improved broiler growth and immune functions, as evidenced by increased body wei

SUBMITTER: Wu Y 

PROVIDER: S-EPMC8318919 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature