Early risk-assessment of patients with nasopharyngeal carcinoma: the added prognostic value of MR-based radiomics.

ABSTRACT:

Objectives

To assess the additive prognostic value of MR-based radiomics in predicting progression-free survival (PFS) in patients with nasopharyngeal carcinoma (NPC) METHODS: Patients newly diagnosed with non-metastatic NPC between June 2006 and October 2019 were retrospectively included and randomly grouped into training and test cohorts (7:3 ratio). Radiomic features (n=213) were extracted from T2-weighted and contrast-enhanced T1-weighted MRI. The patients were staged according to the 8^th edition of American Joint Committee on Cancer Staging Manual. The least absolute shrinkage and selection operator was used to select the relevant radiomic features. Univariate and multivariate Cox proportional hazards analyses were conducted for PFS, yielding three different surviva

SUBMITTER: Kim MJ 

PROVIDER: S-EPMC8319024 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature